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Integral membrane proteins

def: proteins that are directly attached to the bilayer can be removed only by disrupting the bilayer with detergents.

Inositol Phospholipid (chapter 16)

def: Minor lipid components of plasma membranes that contain phosphorylated inositol derivatives; important both for distinguishing different intracellular membranes and for signal transduction in eukaryotic cells.

Inositol 1,4,5-triphosphate (IP3) (chapter 16)

def: small intracellular signaling molecule produced during activation of the inositol phospholipid signaling pathway; causes Ca2+ release from the endoplasmic reticulum.

Intracellular Signaling Molecule (chapter 16)

def: molecule (usually a protein) that is part of the mechanism for transducing and transmitting signals inside a cell.

Intracellular Signaling Pathway (chapter 16)

def: The set of proteins and small-molecule second messengers that interact with each other to relay a signal from the cell membrane to its final destination in the cytoplasm or nucleus.

Intermediate Filament (chapter 17)

def: Fibrous protein filament (~10nm in diameter) that forms rope-like networks in animal cells. Often used as a structural element that resists tension applies to the cell from outside.

Initiator tRNA (chapter 7)

def: Special tRNA that promotes the proper association of ribosomes with mRNA and is required for the initiation of protein synthesis.

Intron (chapter 7)

def: Noncoding region of a eukaryotic gene that is transcribed into an RNA molecule that is then excised by RNA splicing to produce mRNA.

In Situ Hybridization (chapter 10)

def: Technique in which a single-stranded RNA or DNA probe is used to locate a gene or an mRNA molecule in an entire cell or tissue.

Interphase (chapter 18)

def: Long period of the cell cycle between one mitosis and the next. Includes G1 phase, S phase and G2 phase.

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